Invited speaker: Jenny Karousou, Assoc. Professor in Biochemistry, School of Medicine, Department of Medicine and Chemistry, University of Insubria, Italia
Date: Wednesday, May 21, 2025
Time: 12.00
Place: Seminar room, Department of Chemistry [north building, basement]
TITLE: Hyaluronan in the cancer cells microenvironment

Abstract

Hyaluronan (HA) is a glycosaminoglycan of the extracellular matrix with a great role in the homeostasis of the tissues. In the last decades, many research studies are dedicated at the metabolism of HA and how alteration in size and quantity can affect cellular functions in cancer.

The research group of the laboratory in Biochemistry of the School of Medicine at the University of Insubria in Italy studies the role of specific extracellular matrix proteins, exosomes and epigenetic modifications in the metabolism of HA in breast cancer cells. This presentation is based on this research project and includes also a brief presentation of the collaboration between the Universities of Insubria and Patras.

Ass. Prof. J. Karousou - Abstract

Η δημόσια υποστήριξη της Διδακτορικής Διατριβής του Υποψήφιου Διδάκτορα του Τμήματος Χημείας, κ. Χατζόπουλου Αθανάσιου με τίτλο: "Μελέτη της Στόχευσης του Συστήματος Υαλουρονικού/CD44 στον Καρκίνο" θα πραγματοποιηθεί την Παρασκευή 21 Μαρτίου 2025 και ώρα 15:00 μέσω τηλεδιάσκεψης από την πλατφόρμα ZOOM στον σύνδεσμο: https://upatras-gr.zoom.us/j/98683002948?pwd=j8HzM7WjJhICWgjdk9dibysFX5LuMP.1

Η Τριμελής Συμβουλευτική Επιτροπή

Σπ. Σκανδάλης, Αναπλ. Καθηγητής, Επιβλέπων (Πανεπιστήμιο Πατρών)

P. Heldin, Professor (Uppsala University)

Ν. Καραμάνος, Καθηγητής (Πανεπιστήμιο Πατρών)

On Wednesday, March 26, at 13.00 at the ZOOM link https://upatras-gr.zoom.us/j/92961310843?pwd=NB0M9Wh6T1QaY7i0G6RDFtKfkTNga0.1,

an Invited talk by Dr. K. Kolliopoulos will take place.

Invited speaker: Dr. Konstantinos Kolliopoulos, post-doctoral fellow at the Laboratory of Cellular Metabolism and Metabolic Regulation, VIB/KU Leuven, Belgium

Title: Unraveling the role of methionine restriction in breast cancer metastasis

Abstract: Metastasis is the leading cause of mortality among cancer patients. Unfortunately, metastatic breast cancer remains incurable. Metastasis formation includes cancer cell dissemination from the primary tumor, survival in circulation and seeding at distant organs. Cancer cells rely heavily on available nutrients to achieve this process. Thus, dietary interventions are considered as potent cancer therapy strategies and may be appealing to patients, who feel they can contribute to their own treatment. For example, restriction of the non-essential-amino-acids serine and glycine is currently tested in patients with advanced rectal and pancreatic cancer. In contrast, there is a gap of knowledge on the impact of restriction of essential-amino-acids (EAAs) on metastatic cancers, which has the advantage that cancer cells are unable to synthesize them. One of these EAA is methionine, and cancer cells show higher uptake rates than adjacent tissues, promoting tumor growth and chemoresistance. Moreover, methionine restriction restrains obesity and ageing, two major risk factors for metastatic breast cancer. However, how methionine restriction affects breast cancer metastasis remains elusive. In this seminar, I will discuss how dietary methionine restriction affects breast cancer metastasis using cell lines and mouse models and unravel the mechanisms for methionine-dependent metastatic seeding.

For details, see the attached file.

Dear all,

Please, find attached the timetable of Spring semester lecturs of the JMSc programme in Applied Biochemistry.

For the presentations of Research Directors of NCSR “Demokritos”

Join Zoom Meeting

https://us02web.zoom.us/j/82420799993

Meeting ID: 824 2079 9993

In the last page, you can laso find the timetable for written examinations and presentations.

D. Vynios

 2024-2025 Spring semester full timetable

Dear all,

The MSc student Sylvia Maggani will present her Thesis on Wednesday, February 19, at 9.30.

For further detail, please, see the attached file.

On behalf of Prof. N. Karamanos

--

Demitrios H. Vynios

Professor of Connective Tissue Biochemistry Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group Department of Chemistry University of Patras,

26504 Patras, Greece

Tel.: GR+2610997914

 MSc Thesis Presentation-S. Maggani

Dear all,

Please, find attached the abstracts of the seminars of MSc students, which will take place on 17-2-25, starting at 09.00.

For details, please, see the attached files.

--

Demitrios H. Vynios

Professor of Connective Tissue Biochemistry Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group Department of Chemistry University of Patras,

26504 Patras, Greece

Tel.: GR+2610997914

Ραπασάρδου Διονυσία

Μαρία Καρτάλη

SPANOPOULOS K

MARIA GEORGIA DROSINOU

Mineschou Aikaterini Eleftheria

Marios Vetoulas

Stelios Astaras

Dear all,

Please, find attached the abstract of the seminar of MSc student Maria Kyriazopoulou, which will take place on 12-2-25 at 11.30 (Greek time).

Supervisor: Prof. A. TTheocharis

--

Demitrios H. Vynios

Professor of Connective Tissue Biochemistry Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group Department of Chemistry University of Patras,

26504 Patras, Greece

Tel.: GR+2610997914

 Seminar - Maria Kyriazopoulou

Dear all,

Please, find attached the abstract of the seminar of MSc student Aggeliki Natsiou, which will take place on 12-2-25 at 11.00 (Greek time).

Supervisor: Dr. Chrysostomi Gialeli, Researcher

--

Demitrios H. Vynios

Professor of Connective Tissue Biochemistry Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group Department of Chemistry University of Patras,

26504 Patras, Greece

Tel.: GR+2610997914

Seminar-Natsiou Angeliki

Αγαπητοί/ές,

Στο επισυναπτόμενο αρχείο θα βρείτε το πρόγραμμα εξετάσεων για το χειμερινό εξάμηνο του ΔΠΜΣ Εφαρμοσμένης Βιοχημείας..

Demitrios H. Vynios

Professor of Connective Tissue Biochemistry

Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research

Group

Department of Chemistry

University of Patras,

26504 Patras, Greece

Tel.: GR+2610997914

Examination schedule 2024-25

Dear all,

In the attached files you can find the abstracts of the seminars that will be presented on January, 28, by students supervised by Prof. N.

Karamanos of Joint post-graduate programme in Applied Biochemistry.

On behalf of Prof. Karamanos

--

Demitrios H. Vynios

Professor of Connective Tissue Biochemistry Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group Department of Chemistry University of Patras,

26504 Patras, Greece

Tel.: GR+2610997914

Seminar Gourdoupi

Seminar Koletsis

Seminar Kremmydas

Seminar Mangani